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英语和生物都好的天才来帮我我有到问题,不知应该怎么答.Ifthe"message"containedonmRNAisalteredbyamutationoftheDNA,whatmightbetheeffectsonproteinproduction?我懂意思的,就是要用英语怎么回答。
题目详情
英语和生物都好的天才来帮我
我有到问题,不知应该怎么答.
If the "message" contained on mRNA is altered by a mutation of the DNA,what might be the effects on protein production?
我懂意思的,就是要用英语怎么回答。
我有到问题,不知应该怎么答.
If the "message" contained on mRNA is altered by a mutation of the DNA,what might be the effects on protein production?
我懂意思的,就是要用英语怎么回答。
▼优质解答
答案和解析
it depends on what kind of mutation it is.For example,mutation can be point mutation,insertion,or deletion.
Generally speaking,for point mutation,silence mutation causes no change in protein product because the altered DNA encodes same amino acid,mis-sense mutation codes different amino acid in the protein product,and non-sense mutation introduces pre-mature stop coden and therefore usually leads to truncation of final protein product.
Insertion and deletion can cause frame-shifting,which may significantly alter the final protein product.
大致就这样吧,懒得写了,对你的题目来说,大部分情况应该都包括进去了
再加一句,if mutation occurs in 3'UTR or 5'UTR,there is no change in the final protein product.In stead,mutation in those regions might affect the stability of mRNA as well as the efficiency of translation.
还有,四楼所说的隐含子和外显子是什么?intron and exon吗?都mRNA了,哪里来的intron,但凡能在mRNA里面出现的序列,就不能叫intron
Generally speaking,for point mutation,silence mutation causes no change in protein product because the altered DNA encodes same amino acid,mis-sense mutation codes different amino acid in the protein product,and non-sense mutation introduces pre-mature stop coden and therefore usually leads to truncation of final protein product.
Insertion and deletion can cause frame-shifting,which may significantly alter the final protein product.
大致就这样吧,懒得写了,对你的题目来说,大部分情况应该都包括进去了
再加一句,if mutation occurs in 3'UTR or 5'UTR,there is no change in the final protein product.In stead,mutation in those regions might affect the stability of mRNA as well as the efficiency of translation.
还有,四楼所说的隐含子和外显子是什么?intron and exon吗?都mRNA了,哪里来的intron,但凡能在mRNA里面出现的序列,就不能叫intron
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