求翻译下列文字β-抑制蛋白2（Barr2、arrestin3、β-arrestin2)是G蛋白偶联受体家族重要的下游蛋白.它可以通过负向调节多种G蛋白偶联受体（GPCR）的活性实现功能.近年来的研究发现,Barr2还可以通

Question

求翻译下列文字
β-抑制蛋白2（Barr2、arrestin3、β-arrestin2)是G蛋白偶联受体家族重要的下游蛋白.它可以通过负向调节多种G蛋白偶联受体（GPCR）的活性实现功能.近年来的研究发现,Barr2还可以通过发挥脚手架蛋白的作用实现不依赖GPCR的信号转导功能,在代谢疾病,炎症等多种疾病模型中起到重要作用.本论文为了研究β-arrestin2在心脏中的要作用,通过设计实验路线,设计引物,PCR 扩增,酶切,连接目的基因与载体,转化,小提,鉴定和大提等.这些实验方法都根据国内的实验条件进行了优化,并且有一部分还提供了多个备择方案.

Answer 1

β-抑制蛋白2（Barr2、arrestin3、β-arrestin2)是G蛋白偶联受体家族重要的下游蛋白.它可以通过负向调节多种G蛋白偶联受体（GPCR）的活性实现功能.近年来的研究发现,Barr2还可以通过发挥脚手架蛋白的作用实现不依赖GPCR的信号转导功能,在代谢疾病,炎症等多种疾病模型中起到重要作用.
Barr2 (arrestin3、β-arrestin2) is an important downstream protein of the G-Protein Coupling Receptor (GPRS) superfamily. Through negative direction, it can regulate the activity performing functions of various GPRS. According to the research findings of recent years, Barr2’s activity can even be achieved through activating the role of scaffold protein without relying on the signal-transduction functions of GPRS, this plays an important role in many disease models such as metabolic diseases, inflammation, etc.

本论文为了研究β-arrestin2在心脏中的要作用,通过设计实验路线,设计引物,PCR 扩增,酶切,连接目的基因与载体,转化,小提,鉴定和大提等.这些实验方法都根据国内的实验条扩增件进行了优化,并且有一部分还提供了多个备择方案.
In order to study the important role of β-arrestin2 in the heart, this paper designs many experimental methods, such as designing primers, PCR amplification, restriction enzyme, connection of target genes and carriers, conversion, small extraction, identification and large extraction. All these experimental methods have been optimized in accordance with China’s conditions of experimental amplification, and some of them even provide a few option schemes.

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