英语翻译TheT4Ssystemouter-membranecomplex,inadditiontobeingmuchlargerthanpreviouslydescribedouter-membranestructures(forexampleWzaorTolC),isalsoradicallydifferentinshape(SupplementaryFig.9):whereastheWzahomo-octamera

Question

英语翻译
The T4S system outer-membrane complex,in addition to being much larger than previously described outer-membrane structures (for example Wza or TolC),is also radically different in shape (Supplementary Fig.9):whereas the Wza homo-octamer and the homo-TolC trimer are elongated15,17,the hetero-tetradecameric T4S system outer-membrane complex spreads out just under the outer membrane,creating a vast contact area with the inner leaflet of the outer membrane.This contact area is mostly mediated by the TraOCT–TraN complex ring.In effect,the TraOCT–TraN complex ring appears to buttress the entire T4S system against the inner leaflet of the outer membrane,possibly allowing the system to exert much
greater mechanical forces to extrude substrates than would otherwise be feasible in systems like Wza or TolC,which make limited contacts with the inner leaflet of the outer membrane.

Answer 1

该T4S系统外膜复合物,在除了比前面所述外膜结构（例如WZA或TolC外）大得多,也就是在形状完全不同的（补充图9） ：而WZA均聚八聚体和均聚TolC外的三聚体是elongated15,17 ,异tetradecameric T4S系统外膜复合伸展不到外膜,形成与外膜的内小叶广阔的接触面积.该接触区域由TraOCT -TRAN复杂环大多介导的.实际上,TraOCT -TRAN复杂环出现来支持针对外膜的内小叶整个T4S系统,有可能使系统产生多
更大的机械力挤压衬底比其他的像WZA或TolC外系统,这使得与外膜的内小叶有限的接触是可行的.